here are the 49 us ai startups that have raised $100m or more in 2025

The previous year represented a significant period of growth for the artificial intelligence sector, both within the United States and internationally.
According to TechCrunch’s analysis, 49 emerging companies secured funding rounds of $100 million or greater during 2024. Notably, three of these businesses completed multiple substantial funding events, while seven achieved rounds valued at $1 billion or more.
What does the future hold for 2025? As we approach the conclusion of the current year, 2025 has already demonstrated a comparable level of activity to 2024 regarding the number of companies raising $100 million or larger. Furthermore, a considerably higher number of companies have secured multiple funding rounds exceeding $100 million this year in comparison to the previous year.
Below is a list of all U.S.-based artificial intelligence companies that have successfully raised $100 million in funding this year:
November
- Anysphere, the developer of the popular vibe-coding platform Cursor, secured $2.3 billion in a funding event, resulting in a company valuation of $29.3 billion. This announcement, made on November 13th, represents the company’s second funding achievement within the current year.
- Parallel, focused on creating web infrastructure designed for AI agents, completed a $100 million Series A funding round, publicized on November 12th. Index Ventures and Kleiner Perkins jointly spearheaded this investment.
- Hippocratic AI, a startup specializing in artificial intelligence solutions for the healthcare sector, obtained $126 million in a Series C funding round, establishing a company valuation of $3.5 billion. This round, announced on November 3rd and led by Avenir Growth, marks the company’s second funding success this year.
October
- Fireworks AI, a development platform for AI applications utilizing readily available open source models, secured $250 million in Series C funding, as revealed on October 28. This funding round established the company’s valuation at $4 billion.
- Uniphore, an AI solutions provider for businesses, achieved a $2.5 billion valuation following a $260 million Series F funding round publicized on October 22. Investors in this round included Snowflake Ventures, Nvidia, Databricks Ventures, and AMD, among others.
- Sesame, a company specializing in voice AI technology, obtained $250 million in Series B funding, jointly led by Sequoia and Spark Capital. The announcement of this funding occurred on October 21, with SignalRank also contributing to the round.
- OpenEvidence, headquartered in Cambridge, Massachusetts, and focused on creating an AI chatbot for medical applications, completed its second funding effort of 2025. The $200 million Series C round, announced on October 20, resulted in a company valuation of $6 billion.
- Lila Sciences, dedicated to the development of a powerful science-focused AI platform, publicized its second funding round of 2025 on October 14. The $350 million Series A round was co-led by Braidwell and Collective Global.
- Reflection AI, a competitor to DeepSeek, announced its second substantial funding round of the year on October 9. The $2 billion Series B round, led by Nvidia, brought the company’s valuation to $8 billion.
- EvenUp, a provider of AI solutions for the personal injury legal sector, announced a $150 million Series E funding round on October 7, which valued the company at over $2 billion. Bessemer led the round, with participation from Lightspeed, Bain Capital, and SignalFire, among others.
September
- Periodic Labs, developing an artificial intelligence scientist, publicized a $300 million seed funding round on September 30. The investment was spearheaded by Felicis and Andreessen Horowitz, with additional backing from Nvidia, Lightspeed, and Khosla Ventures, among other investors.
- Cerebras Systems, a provider of AI infrastructure solutions, secured a substantial $1.1 billion Series G funding round, establishing the company’s valuation at $8.1 billion. The financing, revealed on September 30, was jointly managed by Fidelity and Atreides Management.
- Modular revealed a $250 million investment round on September 24. The round’s lead investor was US Innovative Technology Fund, with contributions from GV, Greylock, and General Catalyst, and others.
- Distyl AI, focused on building AI-powered software for enterprises, obtained a $175 million Series B funding round, announced on September 23. This funding round resulted in a company valuation of $1.8 billion and included participation from investors such as Khosla Ventures and Lightspeed.
- AI infrastructure company Upscale AI garnered a significant $100 million seed funding round, co-led by Maverick Silicon and Mayfield. The round, publicized on September 17, also featured investments from StepStone Group, Stanford University, and Qualcomm Ventures, among others.
- Groq, specializing in AI inference technology, raised a $750 million Series D-3 funding round, bringing the company’s valuation to approximately $6.9 billion. The round was announced on September 17 and was led by Disruptive.
- AI training startup Invisible Technologies achieved a $2 billion valuation following a $100 million funding round announced on September 16. The investment was spearheaded by Vanara Capital, with participation from Greycroft, Tallwoods Capital, and Freestyle Capital, among others.
- Cognition AI, the creators of the vibe-coding agent Devin, secured a $400 million Series C funding round, announced on September 8. The round was led by Founders Fund and valued the company at $10.2 billion.
- AI Infrastructure company Baseten raised a $150 million Series D funding round, resulting in a company valuation of $2.1 billion. The September 5 round was led by Bond, with participation from CapitalG, IVP and Spark Capital, among others.
- Bret Taylor’s customer service AI agent platform Sierra raised $350 million in a funding round led by Greenoaks Capital. This investment, announced on September 4, valued Sierra at over $10 billion.
- You.com, a provider of a personalized AI search engine, secured a $100 million Series C funding round led by Cox Enterprises. The round was announced on September 3 and valued the company at $1.5 billion.
- AI research lab Anthropic completed its second funding round of 2025 in September. Anthropic announced a $13 billion Series F round on September 2, establishing a company valuation of $183 billion. The round was led by Iconiq, Fidelity, and Lightspeed.
August
- The healthcare and home automation technology company EliseAI secured $250 million in Series E funding, resulting in a company valuation of $2.2 billion. This funding announcement, made on August 20th, was spearheaded by Andreessen Horowitz.
- Decart, a laboratory focused on artificial intelligence research, obtained $100 million in funding and achieved a valuation of $3.1 billion. The investment round, publicized on August 7th, saw participation from Sequoia Capital, Benchmark, and Zeev Ventures, alongside other investors.
July
- The generative media platform Fal secured $125 million in Series C funding, with Meritech Capital Partners taking the lead. The company revealed this funding round on July 31st, establishing a valuation of $1.5 billion. Participants in the round included Salesforce Ventures, Shopify Ventures, Google AI Futures Fund, and additional investors.
- Ambience Healthcare, a five-year-old company developing an AI-driven healthcare operating system, completed a $243 million Series C funding round. Oak HC/FT and Andreessen Horowitz spearheaded the investment. The round also saw contributions from Kleiner Perkins, OpenAI Startup Fund, Smash Capital, and other firms.
- Reka AI, an artificial intelligence research laboratory, obtained $110 million in funding. This Series B round, announced on July 22nd, included investments from Snowflake and Nvidia, and resulted in a company valuation of $1 billion.
- Thinking Machines Lab, an AI research lab, publicly confirmed a $2 billion seed round on July 15th. Andreessen Horowitz led this substantial investment, with participation from Nvidia, Accel, and AMD, among others, bringing the company’s valuation to $12 billion.
- OpenEvidence, headquartered in Cambridge, Massachusetts, is developing an AI-enhanced search solution for medical professionals. The company raised $210 million, achieving a $3.5 billion valuation. The Series B round, announced on July 15th, was led by Kleiner Perkins and GV.
- Harmonic, focused on creating a mathematical reasoning engine, successfully raised $100 million in a Series B funding round. Kleiner Perkins led the investment, which was announced on July 10th and values the company at $875 million.
June
- The healthcare artificial intelligence firm Abridge revealed a $300 million Series E funding round, resulting in a company valuation of $5.3 billion. Andreessen Horowitz spearheaded the investment, with Khosla Ventures also contributing. This marked the company’s second funding event of 2025.
- Harvey, a developer of AI-powered solutions for the legal profession, declared a second $300 million funding round for 2025 on June 23. This recent Series E investment was jointly managed by Kleiner Perkins and Coatue, establishing the company’s worth at $5 billion.
- Tennr, an AI-focused company in the healthcare sector, publicized a $101 million Series C funding round. IVP took the lead on this investment, with contributions from Lightspeed Venture Partners, GV, and Andreessen Horowitz, among others. The funding round resulted in a company valuation of $605 million.
- Glean, a company specializing in enterprise search technology, successfully secured additional funding. On June 10, the company announced a $150 million Series F round, guided by Wellington Management and including participation from Sequoia, Lightspeed Venture Partners, and Kleiner Perkins, among others. Glean’s current valuation stands at $7.25 billion.
- Anysphere, the research and development organization responsible for the AI coding tool Cursor, obtained a substantial $900 million Series C funding round, bringing the company’s valuation to almost $10 billion. Thrive Capital led the investment, with Andreessen Horowitz, Accel, and DST Global also participating.
May
- The artificial intelligence data labeling company Snorkel AI revealed a $100 million Series D funding round on May 29th, establishing a company valuation of $1.3 billion. Addition spearheaded the investment, with contributions from Prosperity7 Ventures, Lightspeed Venture Partners, and Greylock.
- LMArena, a widely-used, community-focused platform for evaluating AI model performance, secured $100 million in seed funding, resulting in a $600 million valuation for the company. The funding announcement came on May 21st and was jointly led by Andreessen Horowitz and UC Investments. Lightspeed Venture Partners, Kleiner Perkins, and Felicis were also involved in the round, alongside other investors.
- TensorWave, an AI infrastructure provider headquartered in Las Vegas, declared a $100 million Series A funding round on May 14th. Magnetar Capital and AMD Ventures co-led the investment, with Prosperity7 Ventures, Nexus Venture Partners, and Maverick Silicon also contributing.
April
- SandboxAQ finalized a $450 million Series E funding round on April 4th, establishing a company valuation of $5.7 billion. This investment round saw participation from prominent entities including Nvidia, Google, and Ray Dalio, the founder of Bridgewater Associates, alongside other investors.
- Runway, a developer of AI models geared towards media creation, secured $308 million in a Series D funding round publicized on April 3rd, resulting in a $3 billion valuation for the company. General Atlantic spearheaded the investment, with additional contributions from SoftBank, Nvidia, and Fidelity.
March
- The prominent artificial intelligence firm OpenAI secured an unprecedented $40 billion in funding, establishing a company valuation of $300 billion. This financing, finalized on March 31, was spearheaded by SoftBank, with additional investment from Thrive Capital, Microsoft, and Coatue, among other entities.
- On March 25, Nexthop AI, a company specializing in AI infrastructure, declared the completion of a Series A funding round guided by Lightspeed Venture Partners. The $110 million investment also drew contributions from Kleiner Perkins, Battery Ventures, and Emergent Ventures, and others.
- Insilico Medicine, headquartered in Cambridge, Massachusetts, obtained $110 million to advance its drug discovery platform powered by generative AI, as revealed on March 13. This Series E round resulted in a $1 billion valuation for the company and was jointly managed by Value Partners and Pudong Chuangtou.
- Celestial AI, a provider of AI infrastructure solutions, successfully raised $250 million in a Series C funding round, achieving a company valuation of $2.5 billion. The financing, which concluded on March 11, was led by Fidelity, with participation from Tiger Global, BlackRock, and Intel CEO Lip-Bu Tan, among others.
- Lila Sciences secured $200 million in a seed funding round as it endeavors to develop a highly advanced science intelligence platform. The round was led by Flagship Pioneering. The Cambridge, Massachusetts-based organization also benefited from investments from March Capital, General Catalyst, and ARK Venture Fund, among others.
- Reflection.Ai, a Brooklyn-based company focused on creating highly intelligent autonomous systems, garnered $130 million in a Series A funding round, resulting in a $580 million valuation for the one-year-old enterprise. Lightspeed Venture Partners and CRV led the investment.
- AI-driven coding company Turing finalized a Series E funding round on March 7, valuing the company – which collaborates with large language model businesses – at $2.2 billion. The $111 million round was headed by Khazanah Nasional, with contributions from WestBridge Capital, Gaingels, and Sozo Ventures, among others.
- Shield AI, a startup developing AI-powered defense technologies, raised $240 million in a Series F funding round that was completed on March 6. The round was co-led by L3Harris Technologies and Hanwha Aerospace, with participation from Andreessen Horowitz and the US Innovative Technology Fund, among others, and valued the company at $5.3 billion.
- Anthropic, an AI research organization and developer of large language models, secured $3.5 billion in a Series E funding round, establishing a company valuation of $61.5 billion. The investment, announced on March 3, was led by Lightspeed, with participation from Salesforce Ventures, Menlo Ventures, and General Catalyst, among others.
February
- Together AI, a developer of open-source generative AI and the infrastructure for building AI models, secured $305 million in Series B funding, resulting in a company valuation of $3.3 billion. The financing, completed on February 20, was jointly headed by Prosperity7 and General Catalyst, with contributions from Salesforce Ventures, Nvidia, Lux Capital, and additional investors.
- Lambda, a firm specializing in AI infrastructure, announced a $480 million Series D funding round on February 19. This investment established the startup’s value at approximately $2.5 billion and was co-led by SGW and Andra Capital. Nvidia, G Squared, ARK Invest, and other entities were also involved in the funding.
- On February 17, Abridge, an AI-powered platform focused on transcribing discussions between healthcare providers and patients, achieved a $2.75 billion valuation through a $250 million Series D funding round. The round was jointly led by IVP and Elad Gil, with participation from Lightspeed, Redpoint, Spark Capital, and various other investors.
- Eudia, a company applying AI to the legal field, obtained $105 million in Series A funding, with General Catalyst taking the lead. The investment also included contributions from Floodgate, Defy Ventures, and Everywhere Ventures, alongside a number of venture capital firms and individual investors, closing on February 13.
- EnCharge AI, a startup developing AI hardware, successfully raised $100 million in a Series B funding round, finalized on February 13. Tiger Global spearheaded the round, with participation from Scout Ventures, Samsung Ventures, and RTX Ventures, among others. The company, headquartered in Santa Clara, was established in 2022.
- Harvey, an AI-driven legal technology company, secured $300 million in Series D funding, valuing the company at $3 billion after just three years of operation. The round, announced on February 12, was led by Sequoia, with contributions from OpenAI Startup Fund, Kleiner Perkins, Elad Gil, and other investors.
January
- The synthetic voice technology firm ElevenLabs secured $180 million in Series C funding, bringing the company’s valuation to over $3 billion. This announcement was made on January 30th, with Iconiq and Andreessen Horowitz serving as co-leaders of the funding round. Additional investors included Sequoia, NEA, Salesforce Ventures, and several others.
- Hippocratic AI, focused on creating extensive language models specifically for healthcare applications, revealed a $141 million Series B funding round on January 9th. This investment resulted in a company valuation exceeding $1.6 billion, with Kleiner Perkins leading the round. Andreessen Horowitz, Nvidia, and General Catalyst were also among the participating investors.
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This article was revised on April 23, June 18, August 27 and November 26 to incorporate additional funding information.
This article has been updated to reflect that Abridge originated in Pittsburgh, rather than being currently based there.